7/22/2023 0 Comments Download cluco d for diabetesThese findings are highly relevant considering that obesity is one of the main risk factors of diabetes. L-Arg supplementation was also shown to reduce adiposity and improve insulin sensitivity in animal models of obesity as well as in patients with diabetes and obesity. Furthermore, investigations in rats have demonstrated that L-Arg can reduce plasma glucose levels, improving glucose tolerance. L-Arg is a powerful secretagogue of the endocrine system, as it induces the secretion of insulin and glucagon, which are protagonists in glucose metabolism. Several studies advocate the implementation of L-Arg for the treatment of diabetes, both directly and indirectly. The intake of L-Arg has been shown to improve oxidative metabolism, through an enhanced mitochondrial function, eventually improving physical performance. L-Arg promotes the secretion of growth hormone from the pituitary gland and is implicated in T cell proliferation and host immune responses. Moreover, L-Arg is involved in the synthesis of creatine, L-Ornithine, L-Glutamate, collagen, polyamines, and agmatine. It is elemental to produce NO, which acts as a major vasodilator with favorable effects on the cardiovascular system. L-Arg is a natural constituent of food proteins. L-Arg is an essential or conditionally essential amino acid - because it can be synthesized by healthy individuals but not by premature newborns - that has been shown to be safe for the human body. Steiger in 1886, who called it “áργυρος” (argiros), a Greek word meaning silver, due to the white-silverish appearance of its crystal. L-Arginine, hereinafter referred to as L-Arg, was first isolated from lupin seeds by E.
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